services.pipewire = {
    enable = true;
    alsa = {
      enable = true;
      support32Bit = true;
    };
    jack.enable = true;
    pulse.enable = true;
    wireplumber.enable = true;

    extraConfig = {
      pipewire."10-rt.conf" = {
        "context.modules" = [
          {
            name = "libpipewire-module-rt";
            args = {
              "rt.prio" = 99;
            };
            flags = [ "ifexists" "nofail" ];
          }
        ];
      };
    };
  };

In reply to @magnetophon:matrix.org
I have a bunch of audio PR's open.
Anyone care to have a look and possibly merge?
https://github.com/NixOS/nixpkgs/pull/444337
https://github.com/NixOS/nixpkgs/pull/466323
https://github.com/NixOS/nixpkgs/pull/469717

There's a few more, but these are the most important ones.
Thanks!

I have this weird thing here:

  services.pipewire = {
    pulse.enable = true;
    jack.enable = true;
    alsa.enable = true;
    extraConfig.pipewire-pulse = {
      tascam."pulse.cmd" = [
        { cmd = "load-module";
          # args = "module-alsa-source source_name=foo device=usbstream:CARD=US122L fragments=3 fragment_size=512";
          args = "module-alsa-sink device=usbstream:0 sink_name=US122L_Out sink_properties=device.description=US122L_Out";
          flags = [ ];
         }
      ];
    };
  };

But when I do systemctl --user restart pipewire-pulse it says in the logs:

Dez 14 17:41:59 thnixpad pipewire[12258]: spa.alsa: 'usbstream:0': playback open failed: No such file or directory