repeating my question from #staging:nixos.org here:

Is anyone from the Gnome team already working on a Gnome 50 PR? There doesn't seem to be one yet, but I'd rather double check before giving it a try myself

And if that is not the case and you are possibly willing to let me have a try at it, is the workflow described in nonemast still up to date?

Nixpkgs GNOME maintainers have the following workflow: When an alpha of a new GNOME release is published, they use update.nix script to automatically bump all GNOME packages in Nixpkgs on the gnome branch. After that, they walk through the commits, reading the release notes and modifying the package expressions as necessary. To have clean Git history where each commit points to a non-broken tree, maintainers push fixup/squash commits. Those are then periodically integrated by rebasing with auto-squashing.