In reply to @grimmauld:grapevine.grimmauld.de
tbh i can't reproduce the issue and i am not familiar enough with pie+asan to judge the impact of just force-disabling asan in audit. unless anyone else has any ideas and/or strong opinions, i'll leave it as is. Willi Butz would you maybe open an upstream issue report?

diff --git a/pkgs/by-name/au/audit/package.nix b/pkgs/by-name/au/audit/package.nix
index 215cda4ba459..71bedbc56352 100644
--- a/pkgs/by-name/au/audit/package.nix
+++ b/pkgs/by-name/au/audit/package.nix
@@ -75,6 +75,9 @@ stdenv.mkDerivation (finalAttrs: {
     libcap_ng
   ];
 
+  # audit is built with asan, and asan breaks with pie on some kernels
+  hardeningDisable = [ "pie" ];
+
   configureFlags = [
     # z/OS plugin is not useful on Linux, and pulls in an extra openldap
     # dependency otherwise

Willi Butz could you try this one too maybe (on the machine that breaks)?

diff --git a/pkgs/by-name/au/audit/package.nix b/pkgs/by-name/au/audit/package.nix
index 215cda4ba459..f4dbb79518be 100644
--- a/pkgs/by-name/au/audit/package.nix
+++ b/pkgs/by-name/au/audit/package.nix
@@ -75,6 +75,9 @@ stdenv.mkDerivation (finalAttrs: {
     libcap_ng
   ];
 
+  # audit is built with asan, and asan breaks with pie on some kernels
+  env.NIX_CFLAGS_COMPILE = "-no-pie";
+
   configureFlags = [
     # z/OS plugin is not useful on Linux, and pulls in an extra openldap
     # dependency otherwise

try this one then, i guess